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  • Gynaecological Cancer
  • Cervical cancer

Introduction

Cervical cancer

Learn more about cervical cancer including types, symptoms, risk factors, steps to diagnosis and potential treatment options.

What is cervical cancer?

What is cervical cancer?

The cervix is a canal located between your uterus and vagina.3 When you’re pregnant, your cervix helps keep your baby in place until it’s fully developed.3 Cervical cancer can occur when abnormal cells develop in the lining of the cervix and form a tumour.1,2,4 Anyone with a cervix is at risk of developing cervical cancer, this can include persons who identify as straight, lesbian, gay bisexual or transgender.2,5

There are two types of cervical cancer:1,2,4

  • Squamous cell carcinoma (SCC): usually starts in the outer surface of the cervix and is the more common form of cervical cancer
  • Adenocarcinoma usually develops in inner surface of the cervix.2,6 This type of cancer may be difficult to diagnose because it starts high in the cervix and isn't always reached during a cervical screening test2,6

Typically, cervical cancer can present as one or more of the following symptoms:2,4

  • vaginal bleeding between periods, during or after sex, or after menopause
  • pain during sex
  • pelvic pain
  • heavier or longer-lasting periods
  • changes to vaginal discharge, such as unusual colour, smell, or volume

Please note, the above are the more commonly known symptoms of cervical cancer.4,7 If you are experiencing anything unusual or have any concerns, always speak with your doctor.

Cells in the cervix don’t suddenly become cancerous, but the process tends to gradually happen over time.7 

Some known risk factors may contribute to developing cervical cancer, especially exposure to the human papillomavirus (HPV).1,4,6 

HPV is passed via skin-to-skin contact, usually as a sexually transmitted infection.1 Different strains of HPV carry different risks.1 Not everyone with HPV will get cervical cancer, but almost every case of cervical cancer is linked to HPV.8,15

Whilst HPV exposure is a key risk for developing cervical cancer,  it isn’t the only risk that needs to be considered.1,8 Other risk factors include:1,2

  • smoking
  • long-term use of the contraceptive pill gives a small increased risk
  • weakened immune system
  • people whose mother was given DES during pregnancy, an artificial form of oestrogen used between 1939 and 1971

 

There is a HPV vaccine and it has been designed to protect against the known strains of HPV that usually cause cervical cancer.8 Your doctor can also discuss more around how HPV is linked to the risk of cervical cancer.8 They can also advise how to get a HPV vaccine as part of the National Immunisation Program.

An ethnic woman wearing a headscarf and fighting cancer sits on the couch with her mother. She is in the foreground and her mom is behind her, with her arm wrapped around in an embrace, and they're both looking out the window in a quiet moment of contemplation.

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Diagnosis

Diagnosing cervical cancer

At present the most effective way to identify whether someone has cervical cancer is through a cervical screening test (formerly called a PAP smear).2,4 Screening is free in Australia and is recommended every 5 years from the age of 25 to 74.2

If your screening test shows anything out of the ordinary, your GP may refer you to a specialist for more detailed tests, which may include:2,4

  • Colposcopy – your doctor may use a magnifying device called a colposcope to examine your cervix more carefully
  • Biopsy – during a colposcopy, a doctor may take a tissue sample for laboratory analysis

If anything unusual is found from testing, your doctor will talk to you about what it means and the next steps.

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Treatment options

Treatment options for cervical cancer

There are various treatment options avaibale and your doctor will determine the most suitable based on diagnosis and other factors.9,10 Broadly, factors that may influence a treatment approache(s) can be stage of disease, age or whether you would like to have children.10

Treatment options for cervical cancer include:4,9-11

Chemotherapy is an approach to cancer therapy which involves the administration of medicine, usually orally or injection, which is intended to kill cancer cells or minimise their growth and spread. Chemotherapy can be used in conjunction with other cancer treatments.

Chemotherapy

Radiation therapy may be offered in the early stages of cancer treatment or after it has started to spread. There are different radiation therapy techniques that may be suitable for different cancer types at different stages.

Radiation Therapy

Surgical intervention can be used in some cases to remove the cervix, uterus, and surrounding tissue. Your doctor will consider whether surgical intervention is appropriate for you.

Targeted therapy uses medications that are designed to target and help kill or slow the growth of cancer cells.

Targeted Therapy
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Some of the emotions you may experience around a diagnosis and subsequent treatment can include disbelief, anxiety, sadness, anger, and loneliness.12 

It is recommended to speak to your doctor about the side effects you may experience during or after your treatment, and the strategies to manage them.

The following is a guide only, please speak with your doctor on what may be appropriate for you:12,14

  • Aim to maintain a healthy diet.12 You can speak with your clinician regarding the design of a suitable eating plan during your treatment
  • Reach out to support groups and others who  are going through treatment
  • Ask your team about topical treatments for your skin if you have irritation or pain
  • It may help to have a daily diary or journal to record things like side effects
  • Speak to your doctor about ways you may be able to incorporate gentle exercise into your weekly routine
  • Rest where needed - it is important to acknowledge when you are fatigued and have rest days when needed
  • Ask for and accept help from family, friends and neighbours
  • Be open with employers about your treatment and discuss flexible working options if you need them

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Support services

Support services

Cancer Council Australia

Australia's leading cancer charity, Cancer Council aims to lead a cohesive approach to reduce the impact of cancer.

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Australian Gynaecological Cancer Foundation (AGCF)

AGCF funds research into all types of gynaecological cancers to improve screening, treatment, and outcomes for women.

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Australian Cervical Cancer Foundation (ACCF)

ACCF is the only consumer-focused cancer charity in Australia dedicated exclusively to preventing cervical cancer and to supporting all individuals impacted by a cancer in cervix and cervical abnormalities.

Visit website
  1. Choi, et al. Pathogens. 2023;12(2):298. 
  2. Cancer Council Australia [website]. Types of Cancer: Cervical Cancer. Last updated March 2023 [Cited July 2023]. Access: https://www.cancer.org.au
  3. Evbuomwan, O and Chowdhury, YS. National Library of Medicine. StatPearls Publishing LLC [Internet]. Physiology, Cervical Dilation. Treasure island (FL). Last Update: May 2023 [Cited July 2023]. Access from: https://www.ncbi.nlm.nih.gov/books/NBK539881/
  4. Burmeister CA, et al. Tumour Virus Res. 2022 Jun; 13: 200238
  5. Berner, AM. Br J Gen Pract. 2021; 71(709): e614–e625.
  6. Teoh D, et al. Obstet Gynecol. 2020 Apr; 135(4): 869–878.
  7. National Library of medicine. NCBI Bookshelf. Informed Health.org [Internet]. Cervical Cancer: Overview. Cologne, Germany: Institute for Quality and Efficiency in Health Care, 2006. Last Update: Dec. 2017 [Accessed July 2023]. Access from: https://www.ncbi.nlm.nih.gov/books/NBK279259/
  8. Commonwealth of Australia. Department of Health. Human papillomavirus (HPV) [webpage].  July 2022 & 2023 [cited July 2023]. Access from: https://www.healthdirect.gov.au/colds
  9. National Comprehensive Cancer Network. NCCN Guidelines; Cervical Cancer. Version 1.2022, Last updated Oct. 26, 2021 [cited July 2023]. Access from: https://www.nccn.org
  10. Australian Government. Cancer Australia. [webpage]. Cervical Cancer: treatment options. Last updated Sept. 2022 [cited July 2023]. Access from: https://www.canceraustralia.gov.au
  11. Cohen PA, et al. Lancet. 2019;393(10167):169-82.
  12. Cancer Council Australia [website]. Psychosocial care. Last updated July 2022 [cited July 2023]. Access: https://www.cancer.org.au
  13. Cancer Council Australia [website]. Exercise for people living with cancer. Last updated March 2019 [cited July 2023]. Access: https://www.cancer.org.au
  14. Cancer Council Australia [website]. Understanding Chemotherapy. Last updated August 2022 [cited July 2023]. Access: https://www.cancer.org.au
  15. World Health Organisation [website]. Cervical cancer. Last updated Feb. 2022 [cited July 2023]. Access from: https://www.who.int

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Disclaimer:

This website is provided for information purposes only. Nothing on this website is intended to be used as medical advice, or to diagnose, treat, cure or prevent any disease. It should not be used as a substitute for your own health professional's advice. Any medical procedure or treatment carries risks. Before proceeding with treatment, you should discuss the risks and benefits of the treatment with an appropriately qualified health practitioner. Individual treatment outcomes and experiences will vary.

This website is provided for information purposes only. Nothing on this website is intended to be used as medical advice, or to diagnose, treat, cure or prevent any disease. It should not be used as a substitute for your own health professional's advice. Any medical procedure or treatment carries risks. Before proceeding with treatment, you should discuss the risks and benefits of the treatment with an appropriately qualified health practitioner. Individual treatment outcomes and experiences will vary.
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