2022-07-18T00:00:00.000+10:00
Ongoing

Ascent 03

Ascent 03
Breast cancer

A randomized, open-label, phase 3 study of sacituzumab govitecan versus treatment of physician's choice in patients with previously untreated, locally advanced, inoperable or metastatic triple-negative breast cancer whose tumors do not express PD-L1 or in patients previously treated with anti-PD-(L)1 agents in the early setting whose tumors do express PD-L1 (Ascent 03 GS-US-592-6238)

A randomized, open-label, phase 3 study of sacituzumab govitecan versus treatment of physician's choice in patients with previously untreated, locally advanced, inoperable or metastatic triple-negative breast cancer whose tumors do not express PD-L1 or in patients previously treated with anti-PD-(L)1 agents in the early setting whose tumors do express PD-L1 (Ascent 03 GS-US-592-6238)

Trial overview

Topic

Breast cancer

Trial registration

number: NCT05382299

Study details

The primary objective of this study is to compare the progression-free survival (PFS) between sacituzumab govitecan-hziy (SG) versus treatment of physician's choice (TPC) in participants with previously untreated, locally advanced, inoperable or metastatic triple-negative breast cancer whose tumors do not express programmed cell death ligand 1 (PD-L1) or in participants previously treated with anti-programmed cell death (ligand or protein) 1 (Anti-PD-(L)1) Agents in the early setting whose tumors do express PD-L1.

Further information

Please click here for more information

Location

GenesisCare North Shore – PI: Sally Baron-Hay

GenesisCare North Shore – PI: Sally Baron-Hay :::

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