Palliative care describes personalised care that’s designed to help people with a progressive or life-limiting illness live as well as possible.2 By helping people manage their physical symptoms, as well as other emotional or social needs, palliative care aims to maintain their quality of life.2
In patients with cancer, palliative care to help relieve or control symptoms can involve medication, surgery, radiation therapy, or a combination of these.2 Your care team will work with you to determine which approach is right for you.
What is palliative radiation therapy?
Palliative radiation therapy is radiation therapy given to patients with advanced or incurable cancer who seek to reduce or relieve cancer symptoms.1 It does not aim to cure cancer; instead, the goal is to help shrink or slow growth of the cancer and to help relieve or control symptoms caused by the cancer – aiming to maintain or improve quality of life.1
Why have palliative radiation therapy?
Palliative radiation therapy is used for a range of reasons including:
- Relieving pain associated with cancer that has spread (metastasised) to bones1,3,4
- Relieving pain caused by spinal cord compression, as well as reducing symptoms such as muscle weakness, impaired mobility, and loss of bowel or bladder function1,3,5
- Reducing symptoms caused by cancer that has spread (metastasised) to the brain, such as headaches, nausea, and seizures1,3,6
- Relieving pressure or blockages in tubes such as the oesophagus (food pipe) or trachea (windpipe), which can occur with head and neck cancers and are associated with symptoms including difficulty swallowing, chest pain, and shortness of breath1,3,7
- Reducing bleeding, pain, and dysfunction associated with cancers that affect the gastrointestinal and genitourinary systems, such as bowel or rectal cancer, bladder cancer, prostate cancer, and cervical or uterine cancer1,3,8-10
How is palliative radiation therapy delivered?
Palliative radiation therapy can be used in combination with other palliative care options, including surgery, medications, and non-medical palliative care interventions. It can also be delivered alongside active cancer treatments, such as chemotherapy or immunotherapy.2,3
Palliative radiation therapy can be given using different techniques and be delivered in different doses, which may be given in a single visit or over multiple visits.2 As palliative radiation therapy aims to relieve or reduce symptoms, it generally uses shorter treatment courses than radiation therapy that is intended to cure cancer – helping to limit the time and effort needed for patients to receive treatment.1,3,11
Palliative radiation therapy may not be suitable for all patients – it depends on the type, location and size of the cancer being treated, as well as individual patient circumstances and preferences.1,11 Your care team will discuss with you whether palliative radiation therapy is an option for you.
- The Royal Australian and New Zealand College of Radiologists, Faculty of Radiation Oncology. Palliative treatment. Updated July 2020. Available at: https://www.targetingcancer.com.au/treatment-by-cancer-type/palliative-treatment/ (accessed October 2023).
- Cancer Council. Understanding palliative care. August 2021. Available: https://www.cancer.org.au/cancer-information/treatment/palliative-care (accessed October2023).
- Spencer, K., Parrish, R., Barton, R., & Henry, A. (2018). Palliative radiotherapy. BMJ, 360, k821. https://doi.org/10.1136/bmj.k821
- Lutz, S., Balboni, T., Jones, J., et al. (2017). Palliative radiation therapy for bone metastases: Update of an ASTRO evidence-based guideline. Practical Radiation Oncology, 7(1), 4–12. https://doi.org/10.1016/j.prro.2016.08.001
- Rades, D., Šegedin, B., Conde-Moreno, A. J., et al. (2016). Radiotherapy with 4 Gy × 5 versus 3 Gy × 10 for metastatic epidural spinal cord compression: Final results of the SCORE-2 trial (ARO 2009/01). Journal of Clinical Oncology, 34(6), 597–602.
- Gondi, V., Bauman, G., Bradfield, L., et al. (2022). Radiation therapy for brain metastases: An ASTRO clinical practice guideline. Practical Radiation Oncology, 12(4), 265–282. https://doi.org/10.1016/j.prro.2022.02.003
- Welsch, J., Kup, P. G., Nieder, C., Khosrawipour, V., Bühler, H., Adamietz, I. A., & Fakhrian, K. (2016). Survival and symptom relief after palliative radiotherapy for esophageal cancer. Journal of Cancer, 7(2), 125–130. https://doi.org/10.7150/jca.13655
- Cameron, M. G., Kersten, C., Vistad, I., van Helvoirt, R., Weyde, K., Undseth, C., ... & Guren, M. G. (2016). Palliative pelvic radiotherapy for symptomatic rectal cancer–a prospective multicenter study. Acta oncologica, 55(12), 1400-1407.
- Raby, S. E. M., Hoskin, P., & Choudhury, A. (2020). The role of palliative radiotherapy in bladder cancer: a narrative review. Annals of palliative medicine, 9(6), 4294–4299. https://doi.org/10.21037/apm-20-1347
- Cameron, M. G., Kersten, C., Guren, M. G., Fosså, S. D., & Vistad, I. (2014). Palliative pelvic radiotherapy of symptomatic incurable prostate cancer–a systematic review. Radiotherapy and Oncology, 110(1), 55-60.
- Lutz, S. T., Jones, J., & Chow, E. (2014). Role of radiation therapy in palliative care of the patient with cancer. Journal of Clinical Oncology, 32(26), 2913-2919.
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