Cancer
KEYNOTE-992
Assess the antitumor efficacy and safety of pembrolizumab in combination with chemoradiotherapy (CRT) versus CRT alone in participants with muscle-invasive bladder cancer (MIBC).
Trial overview
Topic
Bladder cancer
Description
A Phase 3, Randomized, Double-blind, Placebo-controlled Clinical Trial to Study the Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Chemoradiotherapy (CRT) versus CRT Alone in Participants with Muscle-invasive Bladder Cancer (MIBC).
Eligibility criteria
- Muscle Invasive bladder cancer
- Not planned for surgery
Study details
The treatment involves immunotherapy plus chemotherapy plus radiotherapy vs the standard of care, chemotherapy with radiotherapy. While on treatment there will be regular blood tests, urine tests, cystoscopies, and scans to monitor progress. At completion of treatment the study will continue to follow your progress.
Further information
For more information regarding this clinical trial click here.
Location