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      Prostate cancer

      Prostate cancer
      2026-07-09T00:00:00.000+10:00

      ACTfirst 

      ACTfirst 
      Prostate

      A phase III, open-label, multi-center, randomized study comparing AAA817 plus ARPI versus standard of care in adult participants with PSMA-positive metastatic castration resistant prostate cancer

      A phase III, open-label, multi-center, randomized study comparing AAA817 plus ARPI versus standard of care in adult participants with PSMA-positive metastatic castration resistant prostate cancer.

      Trial overview

      Clinical Area

      Theranostics

      Disease

      Prostate

      Disease site

      Genitourinary (GU)

      Study Phase

      III

      Trial Identifiers

      Registration number: NCT06855277

      https://clinicaltrials.gov/study/NCT06855277

      GenesisCare Location(s)
      St John of God Hospital, Murdoch
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      St John of God Hospital, Murdoch, 100 Murdoch Drive, Murdoch, WA, 6150, Australia

      phone icon (08) 9366 1500 email icon receptiononcologymurdoch@genesiscare.com
      WA
      St John of God Hospital, Murdoch
      /au/our-centres/wa-st-john-of-god-hospital-murdoch
      Find out more Get directions
      South Terrace (Radiation Oncology)
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      Level 1, 337 South Terrace, Adelaide, SA, 5000, Australia

      phone icon (08) 8228 6700 email icon infooncologysa@genesiscare.com
      SA
      South Terrace (Radiation Oncology)
      /au/our-centres/st-andrews-adelaide-oncology
      Find out more Get directions
      Cabrini Hospital, Malvern
      location pin icon

      Cabrini Hospital Malvern, Level B4, Gandel Wing, 183 Wattletree Road, Malvern, VIC, 3144, Australia

      phone icon (03) 9597 6900 email icon cabrinireception@genesiscare.com
      VIC
      Cabrini Hospital, Malvern
      /au/our-centres/cabrini-gandel-wing
      Find out more Get directions
      Principal Investigator(s)
      Nuclear Medicine Physician

      Prof. Joe Cardaci

      MBBS, FRACP, AANNMS

      Prof. Joe Cardaci
      Joe
      Cardaci
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      Profile Image - Prof. Joe Cardaci
      Medical Oncologist

      Dr Tony Michele

      MBBS FRACP

      Dr Tony Michele
      Tony
      Michele
      View Profile
      Profile Image - Dr Tony Michele
      Nuclear Medicine Physician

      A/Prof Dinesh Sivaratnam

      MBBS FRACP FAANMS, B.Med.Sci.

      A/Prof Dinesh Sivaratnam
      Dinesh
      Sivaratnam
      View Profile
      Profile Image - A/Prof Dinesh Sivaratnam

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