2024-02-13T00:00:00.000+11:00
Ongoing

Ascent 07

Ascent 07
Breast cancer

Study of Sacituzumab Govitecan Versus Treatment of Physician's Choice in Patients with Hormone Receptor-positive/Human Epidermal Growth Factor Receptor 2 Negative (HR+/HER2-) Metastatic Breast Cancer Who Have Received Endocrine Therapy.

Study of Sacituzumab Govitecan Versus Treatment of Physician's Choice in Patients with Hormone Receptor-positive/Human Epidermal Growth Factor Receptor 2 Negative (HR+/HER2-) Metastatic Breast Cancer Who Have Received Endocrine Therapy.

Trial overview

Topic

Breast cancer

Eligibility criteria

Inclusion criteria:

  • 18 Years and older
  • All genders
  • Documented evidence of HR+ metastatic breast cancer (mBC) confirmed with the most recently available tumor biopsy from a locally recurrent or metastatic site.
  • Documented evidence of HER2- status.
  • ECOG 0-1

For further inclusions please click on further information below.

Exclusion Criteria:

Prior treatment with HMBD-001, docetaxel, cetuximab or any other agent that targets Epidermal Growth Factor Receptor (EGFR) or HER3, including pan-HER inhibitors

Study details

The goal of this clinical study is to see if sacituzumab govitecan-hziy (SG) can improve life spans of people with HR+/HER2- metastatic breast cancer and their tumor does not grow or spread when compared to current available standard treatments, such as paclitaxel, nab-paclitaxel or capecitabine. The primary objective is to compare the effect of SG relative to the treatment of physician's choice (TPC) on progression-free survival (PFS).

Further information

Please click here for more information

Location
Northshore :::

Brisbane – ICON Cancer Clinic South Brisbane

Brisbane – ICON Cancer Clinic South Brisbane :::

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