177Lutetium PSMA therapy

177Lutetium PSMA therapy can be used to treat advanced prostate cancer. Over time prostate cancer can become resistant to hormone therapy.

 

177Lutetium PSMA therapy, or Prostate-Specific Membrane Antigen therapy, is an innovative molecular therapy used to treat advanced prostate cancer. It’s one of a group of treatments known as Peptide Receptor Radionuclide Therapy (PRRT). It precisely targets cancerous cells, avoiding damage to surrounding healthy tissue.

How does 177Lutetium PSMA therapy work?

PSMA is a type of protein located on the surface of a cell. It’s found on the prostate gland.

If you have prostate cancer, you’ll have more PSMA than normal. If the prostate cancer has spread to other parts of the body (metastasised), the PSMA will also be there.

177Lutetium PSMA therapy uses a molecule which attaches itself to the PSMA receptors on the cancer cells. Before it’s given to you, the PSMA molecule is bound with 177Lutetium. This is a radioactive substance. It damages and destroys prostate cancer cells in a targeted way, with minimal damage to healthy cells. The PSMA molecule carries the 177Lutetium straight to the tumour site so your whole body isn’t exposed to radiation.

Why would I be offered this treatment?

You may be offered 177Lutetium PSMA therapy if your prostate cancer has spread and other therapies have failed.

This therapy helps:

  • Reduce the size of the tumour and stop it growing
  • Improve your symptoms
  • Maintain and improve quality of life

After treatment, some patients have a long period of remission and significant improvements in their quality of life, but it doesn’t cure your cancer.

Further information

Before you start treatment, you’ll have a diagnostic PET/CT scan. The scan identifies the location of the cancer and helps in staging and planning your treatment.

177Lutetium PSMA therapy is an outpatient procedure in our Theranostics suite. Your treatment will be delivered over four hours by a drip inserted into a vein in your arm.

Most people have four treatments carried out 6-8 week apart. Your therapy will be personalised according to your response and symptoms.

177Lutetium is cleared from your body when you urinate, with 60% eliminated within 24 hours of treatment.

Like all cancer treatments, there can be side-effects. These vary from person to person, but may include:

  • Dry mouth
  • Tiredness
  • Mild nausea
  • Loss of appetite

You may also produce fewer blood cells than normal for a while. But you’ll be offered regular blood tests to check everything is OK.

We’ll also help you find ways to reduce and manage any side-effects and you may be able to have medication to reduce any symptoms.

Before you start treatment, you’ll have a diagnostic PET/CT scan. The scan identifies the location of the cancer and helps in staging and planning your treatment.

177Lutetium PSMA therapy is an outpatient procedure in our Theranostics suite. Your treatment will be delivered over four hours by a drip inserted into a vein in your arm.

Most people have four treatments carried out 6-8 week apart. Your therapy will be personalised according to your response and symptoms.

177Lutetium is cleared from your body when you urinate, with 60% eliminated within 24 hours of treatment.

Like all cancer treatments, there can be side-effects. These vary from person to person, but may include:

  • Dry mouth
  • Tiredness
  • Mild nausea
  • Loss of appetite

You may also produce fewer blood cells than normal for a while. But you’ll be offered regular blood tests to check everything is OK.

We’ll also help you find ways to reduce and manage any side-effects and you may be able to have medication to reduce any symptoms.

Easy Access

 

Cancer care at GenesisCare may be covered by private medical insurance – we’re recognised by most major insurers. We also offer a range of self-pay packages.
We offer Theranostics at our Windsor Centre, you can choose from a range of appointment times and we can schedule your treatment to suit your needs.

How to find us

Make an enquiry about 177Lutetium PSMA therapy

Whether you’re in need of treatment or would like more information please complete our enquiry form and we will get back to you – usually within 24 hours.

Make an enquiry

DR-Yong

Meet Dr Yong Du

Dr Yong Du
MBBS MSc PhD FRCP

Dr Yong Du is a Consultant Physician in Nuclear Medicine & PET/CT. He has extensive experience in both Diagnostic and Therapeutic Nuclear Medicine and was the first recipient of the UK HEFCE Clinical Senior Lectureship award in the Nuclear Medicine specialty.

Learn more

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