Ovarian cancer

Ovarian cancer is often diagnosed with imaging scans, such as ultrasound and CT, and pathology tests such as blood tests and biopsy, although your doctor may use other tests to identify the problem. You may also have other advanced tests to find out more about your cancer, where it’s located and which treatments are likely to be most effective. Some of these tests are also used to assess how well your treatment is working.

Find your nearest GenesisCare center to find out what diagnostic tests and scans are available in your local area. Whatever your outcome, our expert team will support you throughout your treatment journey.

We work with expert teams of surgeons who are specially trained in surgical removal of tumors in the ovaries. Surgery is the main treatment for many ovarian cancers and there are different procedures available. Your surgeon will recommend the most appropriate one for you depending on how far your cancer has spread and whether you wish to have children in the future.

Unilateral oophorectomy

Your surgeon may recommend removing the affected ovary if your cancer is in a very early stage and has not spread. Unilateral oophorectomy can also be combined with surgery to remove the nearby fallopian tube in a procedure called unilateral salpingo-oophorectomy. If you’re of child-bearing age, these procedures may preserve your ability to have children.

Bilateral oophorectomy

If the ovarian cancer is found in both ovaries but has not spread to the uterus, the ovaries can be removed during a bilateral oophorectomy. Both fallopian tubes may also be resected. If you haven’t undergone menopause, the removal of both ovaries will cause you to experience premature menopause as your body will not produce estrogen and progesterone. You’ll also not able to produce any eggs, but as procedure does not damage the uterus, you may still be able to become pregnant using frozen or donor eggs.

Hysterectomy

The most common surgery for ovarian cancer is hysterectomy and it’s usually used for more advanced cancers that have spread to the uterus, or if you don’t want to become pregnant in the future. During this procedure, your surgeon will remove the ovaries, fallopian tubes and uterus. They may also remove nearby lymph nodes and fatty abdominal tissue called the omentum

External beam radiation therapy (ERBT)

External beam radiation therapy (ERBT) delivers high-powered X-rays from outside the body, precisely targeting and shrinking or destroying tumors. Radiation therapy may be recommended after surgery to destroy any remaining cancer cells and to help prevent a recurrence or slow the growth of the disease.

At GenesisCare we offer fast access to the latest technologies and treatments that have been proven to make a difference. These include:

Intensity-modulated radiation therapy (IMRT)

IMRT is an advanced external beam radiation therapy technique where the beams of radiation are precisely shaped to exactly match your tumor and damage to adjacent healthy tissues is limited.

At GenesisCare, we offer various drug therapies and a wide range of the latest anti-cancer drugs for ovarian cancer treatment, including hormone therapy, chemotherapy and targeted therapy.

Hormone therapy

Many ovarian tumors need the hormone estrogen to grow. Hormone therapy for ovarian cancer works by blocking estrogen from binding to the cancer cells, or preventing your body from producing estrogen, which slows down their growth. Common types of hormone therapy for ovarian cancers are:

• LHRH agonists – stop your ovaries from producing estrogen
• Tamoxifen – stop estrogen from stimulating cancer growth
• Aromatase inhibitors – blocks hormones from turning into estrogen in post-menopausal women

Chemotherapy for ovarian cancer

Chemotherapy refers to drugs that destroy cancer cells. Our expert teams may recommend chemotherapy before or after other treatments, or on its own. The type of chemotherapy you’ll receive will also depend on your how advanced your ovarian cancer is. If you have cancer that has spread to other parts of your body, chemotherapy can help control its growth, relieve symptoms and improve your ovarian cancer prognosis.

Targeted therapy for ovarian cancer

As researchers know more about ovarian cancer, they have developed new treatments that can specifically target it. We use targeted therapy to seek and attack cellular activity that the cancer depends on to survive and grow. They are used depending on the specific genetic make up of your cancer. Types of targeted therapy for ovarian cancer include:

• PARP inhibitors – suitable for certain ovarian cancers, by blocking the DNA repair pathway in cancer cells often leading to cell death
• Angiogenesis inhibitors – appropriate for some ovarian cancers, work by blocking the protein VEGF which promotes new blood vessel formation and helps tumors grow
• NTRK inhibitors – a small number of ovarian cancers have changes in a gene called NTRK which can lead to abnormal cell growth and cancer. These drugs are used for advanced ovarian cancer to target proteins made by these genes

People choose GenesisCare so they can access the latest technologies, effective treatments and personalized care that’s tailored to them without delay.

Cancer treatment and care is constantly evolving and we offer the world’s latest evidence-based treatments that have been shown to benefit patients. By working together closely, our multidisciplinary teams of oncologists, surgeons, radiation therapists and other healthcare specialists provide care that’s focused on you, not just your cancer.

We know that for many people, cancer is a life-changing experience and our goal is to help you through it in the most positive way possible. That’s why as well as offering exceptional cancer treatments, we also provide you with support and resources for your cancer journey—including advice about nutrition and exercise, expert help for managing side effects and information on local support groups.