Ongoing 2020 Michigan & Florida

RTOG 3506

STEEL: A Randomized Phase II Trial of Salvage Radiotherapy with Standard vs Enhanced Androgen Deprivation Therapy (with Enzalutamide) in Patients with PostProstatectomy PSA Recurrences with Aggressive

Trial overview

Disease
Prostate cancer treatment & diagnosis
Topic
RTOG 3506
Description
Primary Objective The primary goal of this study is to determine whether, in men with postprostatectomy PSA (prostate specific antigen) recurrences with aggressive disease features, salvage radiotherapy (SRT) with enhanced androgen deprivation therapy (ADT), consisting of enzalutamide (MDV3100) and a GnRH analog, will improve progression-free survival compared to SRT with standard GnRH analog -based ADT.
Physicians

Dr. Thomas Boike

MD

Radiation Oncologist

Works at 3 centers.

Dr. Larry L. Kestin

MD, FACR

Radiation Oncologist

Works at 3 centers.

Dr. Alvaro A. Martinez

MD, FACR, FABS, FASTRO

Radiation Oncologist

Works at 5 centers.

Dr. Frank A. Vicini

MD, FACR, FASTRO

Radiation oncologist

Works at 3 centers.

Dr. John Vito Antonucci

MD

Radiation Oncologist

Works at 4 centers.

Dr. Michael I. Ghilezan

MD, PhD

Radiation Oncologist

Works at 4 centers.

Dr. Eduardo B. Fernandez

MD, PhD, FACRO, FASTRO

Radiation Oncologist

Works at 4 centers.

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Location
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