Cancer
Cancer Ongoing 2020 Michigan: Maria Pappas (248) 553-0606

EA5181

Randomized Phase III Trial of MEDI4736 (durvalumab) as Concurrent and Consolidative Therapy or Consolidative Therapy Alone for Unresectable

Trial overview

Disease
Lung cancer treatment and diagnosis
Topic
EA5181
Description
Primary Objective:The primary objective of the trial is to determine whether concurrent MEDI4736 (durvalumab) with cytoxic chemo/radiation improves overall survival (OS) in addition to a standard therapy (chemotherapy and radiation followed by consolidative MEDI4736 (durvalumab)). Secondary objectives include estimation of progression-free survival, best objective response, incidence of local/distant progression, and toxicity.Patient Population:Patients with unresectable Stage 3 Non-small cell lung cancer.
Physicians

Dr. Alvaro A. Martinez

MD, FACR, FABS, FASTRO

Radiation Oncologist

Works at 5 centers.

Dr. Frank A. Vicini

MD, FACR, FASTRO

Radiation oncologist

Works at 3 centers.

Dr. Larry L. Kestin

MD, FACR

Radiation Oncologist

Works at 3 centers.

Dr. Thomas Boike

MD

Radiation Oncologist

Works at 3 centers.

Dr. Michael I. Ghilezan

MD, PhD

Radiation Oncologist

Works at 4 centers.

Dr. John Vito Antonucci

MD

Radiation Oncologist

Works at 4 centers.

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Location
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